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IL-18 and Cutaneous Inflammatory Diseases

Authors
Lee, Ji HyunCho, Dae HoPark, Hyun Jeong
Issue Date
Dec-2015
Publisher
MDPI
Keywords
IL-18; psoriasis; atopic dermatitis; urticaria; contact dermatitis; alopecia areata; drug eruption; lupus erythematosus; fibrosis; graft-versus-host disease; skin tumor; skin disease
Citation
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.16, no.12, pp 29357 - 29369
Pages
13
Journal Title
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume
16
Number
12
Start Page
29357
End Page
29369
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/10152
DOI
10.3390/ijms161226172
ISSN
1661-6596
1422-0067
Abstract
Interleukin (IL)-18, an IL-1 family cytokine, is a pleiotropic immune regulator. IL-18 plays a strong proinflammatory role by inducing interferon (IFN)-. Previous studies have implicated IL-18 in the pathogenesis of various diseases. However, it is not well understood biologic activities of IL-18 in the diverse skin diseases. Here, we have reviewed the expression and function of IL-18 in skin diseases including inflammatory diseases. This article provides an evidence-based understanding of the role of IL-18 in skin diseases and its relationship with disease activities.
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대학 > 기초교양대학 > 기초교양학부 > 1. Journal Articles

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