Detailed Information
Cited 0 time in 
Cited 2 time in 
Cited 2 time in
Metadata Downloads
A Chiral Benzyl Group as a Chiral Auxiliary and Protecting Group for the Synthesis of Optically Active 1,2-Diols and (+)-Frontalin
- Issue Date
- 23-Jan-2014
- Publisher
- GEORG THIEME VERLAG KG
- Keywords
- nucleophilic addition; diols; -benzyloxy ketones; (+)-frontalin; stereoselective synthesis
- Citation
- SYNLETT, v.25, no.2, pp 251 - 254
- Pages
- 4
- Journal Title
- SYNLETT
- Volume
- 25
- Number
- 2
- Start Page
- 251
- End Page
- 254
- ISSN
- 0936-5214
1437-2096
- Abstract
- Chelation-controlled asymmetric nucleophilic addition of a Grignard reagent to chiral -benzyloxy ketones gives the corresponding alcohols with high diastereoselectivities (up to 96% de) by 1,4-asymmetric induction. A chiral benzyl group is used as a chiral auxiliary as well as a protecting group for the synthesis of optically active 1,2-diols and (+)-frontalin.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 약학대학 > 약학부 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.