Detailed Information

Cited 0 time in webofscience Cited 8 time in scopus
Metadata Downloads

Laminaria japonica Combined with Probiotics Improves Intestinal Microbiota: A Randomized Clinical Trial

Authors
Ko, Seok-JaeKim, JinsungHan, GajinKim, Seul-KiKim, Hong-GeolYeo, InkwonRyu, BonghaPark, Jae-Woo
Issue Date
Jan-2014
Publisher
MARY ANN LIEBERT, INC
Keywords
Health functional food; Intestine; Probiotics; Seaweeds
Citation
JOURNAL OF MEDICINAL FOOD, v.17, no.1, pp.76 - 82
Journal Title
JOURNAL OF MEDICINAL FOOD
Volume
17
Number
1
Start Page
76
End Page
82
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/11009
DOI
10.1089/jmf.2013.3054
ISSN
1096-620X
Abstract
Laminaria japonica—a widely used ingredient in seaweed kimchi—and lactic acid bacteria (LAB)—a main component of traditional fermented Korean food—may alter human intestinal microbiota composition and have a positiveeffect on various digestive problems. However, few clinical trials have investigated the potential benefits of L. japonica when combined with LAB for human intestinal microbiota. Therefore, this study was designed to evaluate the effects of L. japonica and representative LAB on the human intestine. Forty participants with no known digestive diseases were randomly assigned to one of the two combination groups: (1) L. japonica with LAB and (2) L. japonica with placebo LAB. The study agents were administered for 4 weeks with a 2-week follow-up period. The primary outcome measure was the number of each of the seven LAB species in the human intestine, and the secondary outcome measures included the Korean version of the Gastrointestinal Symptom Rating Scale, the World Health Organization Quality of Life, and bowel functions. The primary outcome was evaluated before and after administration of the study agents (0 and 4 weeks), and the secondary outcomes were evaluated at 0, 4, and 6 weeks. Four of the seven LAB species were found to be significantly increased in the L. japonica with the LAB group and five species were significantly different from those of the placebo group. The secondary outcome measures did not change significantly. In conclusion, L. japonica with LAB facilitated the proliferation of beneficial human intestinal microbiota.
Files in This Item
There are no files associated with this item.
Appears in
Collections
이과대학 > 통계학과 > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Yeo, In Kwon photo

Yeo, In Kwon
이과대학 (통계학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE