Detailed Information
Cited 0 time in 
Cited 4 time in 
Cited 4 time in
Metadata Downloads
Identification of EphA7 BAC clone containing a long-range dorsal midline-specific enhancer
- Authors
- Kim, Yujin; Park, Soochul
- Issue Date
- Feb-2011
- Publisher
- KOREAN SOCIETY BIOCHEMISTRY & MOLECULAR BIOLOGY
- Keywords
- Bacterial artificial chromosome; Enhancer; EphA7; Transgenic mice
- Citation
- BMB REPORTS, v.44, no.2, pp 113 - 117
- Pages
- 5
- Journal Title
- BMB REPORTS
- Volume
- 44
- Number
- 2
- Start Page
- 113
- End Page
- 117
- ISSN
- 1976-6696
1976-670X
- Abstract
- Previous studies suggest that EphA7 plays a critical role in neural tube closure or cortical progenitor apoptosis. In this report, enhancer trap assay was used to modify various EphA7 BAC clones and screen a large genomic region spanning 570 kb downstream of the EphA7 gene. We found that the dorsal midline-specific EphA7 enhancer resides on the 457D20 EphA7 BAC clone and is localized to a 35 kb genomic region in between +345.7 kb to +379.8 kb downstream of the EphA7 transcription start site. Identification of the EphA7 BAC clone containing a long-range dorsal midline enhancer may constitute a useful tool for investigating the biological functions of EphA7 in vivo. [BMB reports 2011; 44(2): 113-117]
- Files in This Item
- Go to Link
- Appears in
Collections - 이과대학 > 생명시스템학부 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.