Evaluation of the Antiangiogenic, Anti-inflammatory, and Antinociceptive Activities of Morin
- Authors
- Jung, Hyun-Joo; Kim, Su-Jung; Song, Yun-Seon; Park, Eun-Hee; Lim, Chang-Jin
- Issue Date
- Feb-2010
- Publisher
- GEORG THIEME VERLAG KG
- Keywords
- morin; antiangiogenic; anti-inflammatory; antinociceptive; endostatin
- Citation
- PLANTA MEDICA, v.76, no.3, pp 273 - 275
- Pages
- 3
- Journal Title
- PLANTA MEDICA
- Volume
- 76
- Number
- 3
- Start Page
- 273
- End Page
- 275
- URI
- https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/13269
- DOI
- 10.1055/s-0029-1186079
- ISSN
- 0032-0943
1439-0221
- Abstract
- Morin displayed significant inhibition of chick chorioallantoic membrane (CAM) angiogenesis and was able to increase the endostatin level in human umbilical vein endothelial cells (HUVECs). Morin was shown to contain an in vivo anti-inflammatory activity using a carrageenan-induced air pouch model in mice. Antinociceptive activity of morin was also assessed using an acetic acid-induced writhing test in mice. Collectively, morin possesses antiangiogenic, in vivo anti-inflammatory, and antinociceptive activities.
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