Meta-analysis of Inline Filtration Effects on Post-infusion Phlebitis Caused by Particulate Contamination of Intravenous AdministrationMeta-analysis of Inline Filtration Effects on Post-infusion Phlebitis Caused by Particulate Contamination of Intravenous Administration
- Other Titles
- Meta-analysis of Inline Filtration Effects on Post-infusion Phlebitis Caused by Particulate Contamination of Intravenous Administration
- Authors
- 구혜민; 이의경; Jiyeon Kim; Sukhyun Kang
- Issue Date
- Aug-2010
- Publisher
- 한국약제학회
- Keywords
- inline filter; phlebitis; intravenous infusion; meta-analysis
- Citation
- Journal of Pharmaceutical Investigation, v.40, no.4, pp 225 - 230
- Pages
- 6
- Journal Title
- Journal of Pharmaceutical Investigation
- Volume
- 40
- Number
- 4
- Start Page
- 225
- End Page
- 230
- URI
- https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/13449
- ISSN
- 2093-5552
2093-6214
- Abstract
- The particulate contamination of intravenously administered fluid has been of major concern. One of the most common complications associated with long term i.v. therapy is post-infusion phlebitis (PIP). We undertook a systematic review and meta-analysis of the effect of inline filters on PIP. An electronic search of Medline, KoreaMed, and KRIST was conducted to identify randomized controlled trials evaluating the effect of inline filters. Meta-analysis was undertaken using STATA 10. A total of 62 literatures were retrieved, of which 7 were included in meta-analysis. Inline filtration for intravenous infusion significantly reduced by 39% of the incidence of phlebitis, with a relative risk of 0.61 (95% CI 0.41-0.90, p=0.012). Therefore, inline filtration is a highly effective means of decreasing the incidence of infusion phlebitis and should be considered as a part of intravenous therapy.
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