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차가버섯 열수 추출물이 비장세포 증식능과 Cytokine 생성능에 미치는 영향Effects of Hot Water Extract of Chaga Mushroom on the Proliferation and Cytokines Production of Mouse Splenocytes In Vitro

Other Titles
Effects of Hot Water Extract of Chaga Mushroom on the Proliferation and Cytokines Production of Mouse Splenocytes In Vitro
Authors
김보라고숙경표명윤
Issue Date
Jun-2010
Publisher
대한약학회
Keywords
Chaga mushroom; Con A; LPS; IFN-γ; IL-4
Citation
약 학 회 지, v.54, no.3, pp 187 - 191
Pages
5
Journal Title
약 학 회 지
Volume
54
Number
3
Start Page
187
End Page
191
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/13471
ISSN
0377-9556
Abstract
Chaga mushroom (Inonotus obliquus) has been identified to have various biological activities. This study was performed to investigate the potential of chaga mushroom as a immunomodulating functional food. When mouse splenocytes were exposed to various concentration of hot water extracts of chaga mushroom (IOE) with mitogens (Con A, LPS), splenocytes proliferation was significantly increased. Also, IFN-γ and IL-4 levels were significantly enhanced. Therefore, our results suggest that chaga mushroom may have the potential of being an immunomodulating functional food.
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