SMALL UBIQUITIN-LIKE MODIFIERS IN CELLULAR MALIGNANCY AND METASTASIS
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Keun Il | - |
dc.contributor.author | Baek, Sung Hee | - |
dc.date.available | 2021-02-22T14:31:38Z | - |
dc.date.issued | 2009-00 | - |
dc.identifier.issn | 1937-6448 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/14039 | - |
dc.description.abstract | Small ubiquitin-like modifiers (SUMOs) mediate a variety of cellular functions of protein targets mainly in the nucleus but in other cellular compartments as well, and thereby participate in maintaining cellular homeostasis. SUMO system plays important roles in transcriptional regulation, DNA damage responses, maintaining genome integrity, and signaling pathways. Thus, in some cases, loss of regulated control on SUMOylation/deSUMOylation processes causes a defect in maintaining homeostasis and hence gives a cue to cancer development and progression, Furthermore, recent studies have revealed that SUMO system is involved in cancer metastasis. In this review, we will summarize the possible role of SUMO system in cancer development, progression, and metastasis and discuss future directions. | - |
dc.format.extent | 47 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER ACADEMIC PRESS INC | - |
dc.title | SMALL UBIQUITIN-LIKE MODIFIERS IN CELLULAR MALIGNANCY AND METASTASIS | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1016/S1937-6448(08)01807-8 | - |
dc.identifier.scopusid | 2-s2.0-59649113473 | - |
dc.identifier.wosid | 000263825900007 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 273, v.273, pp 265 - 311 | - |
dc.citation.title | INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 273 | - |
dc.citation.volume | 273 | - |
dc.citation.startPage | 265 | - |
dc.citation.endPage | 311 | - |
dc.type.docType | Review; Book Chapter | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.subject.keywordPlus | SUMO-SPECIFIC PROTEASE | - |
dc.subject.keywordPlus | NF-KAPPA-B | - |
dc.subject.keywordPlus | GTPASE-ACTIVATING PROTEIN | - |
dc.subject.keywordPlus | CHROMATIN-REMODELING COMPLEX | - |
dc.subject.keywordPlus | INDUCIBLE FACTOR 1-ALPHA | - |
dc.subject.keywordPlus | NUCLEAR-PORE COMPLEX | - |
dc.subject.keywordPlus | E3 LIGASE ACTIVITY | - |
dc.subject.keywordPlus | TRANSCRIPTIONAL REPRESSION | - |
dc.subject.keywordPlus | CONJUGATING ENZYME | - |
dc.subject.keywordPlus | ANDROGEN RECEPTOR | - |
dc.subject.keywordAuthor | SUMO | - |
dc.subject.keywordAuthor | SUMOylation | - |
dc.subject.keywordAuthor | deSUMOylation | - |
dc.subject.keywordAuthor | Ubc9 | - |
dc.subject.keywordAuthor | SENP | - |
dc.subject.keywordAuthor | Cancer | - |
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