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신독성약물 용량조절 시스템의 개발Development of Renal Dosing System at a University Hospital

Other Titles
Development of Renal Dosing System at a University Hospital
Authors
최경숙황수희구현경조유미이은숙이숙향김홍빈장윤석진호준채동완김윤이병구
Issue Date
Dec-2008
Publisher
대한의료정보학회
Keywords
Renal Dosing System; Knowledge‐base; Implementation; Dosage Adjustment Alerting; Renal Dosing System; Knowledge‐base; Implementation; Dosage Adjustment Alerting
Citation
Healthcare Informatics Research, v.14, no.4, pp 373 - 385
Pages
13
Journal Title
Healthcare Informatics Research
Volume
14
Number
4
Start Page
373
End Page
385
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/14403
ISSN
2093-3681
2093-369X
Abstract
Objective: This report is describing the development and implementation process of the knowledge‐based renal dose adjustment system at a university hospital. Method: From the hospital drug formulary which included about 1500 medications, clinical pharmacists selected 243 nephrotoxic medications which require dose adjustment in patients with renal impairment. Through literature review and consultation of clinical pharmacists, nephrologist, and infectious disease specialist, we developed an accordant renal dosing knowledge‐base and used them to build the rules for dosage adjustment alerts and to provide information related to alerts such as patients’age, gender, most recent weight, latest serum creatinine, calculated creatinine clearance, and recommended dosage for renal insufficiency. Status Report: As of August 2006, the renal dosing system which monitored drug prescription and generated real‐time alerting window to help physician to adjust drug doses in patients with renal impairment was implemented and has been operated well since initial implementation. Conclusion: Renal dosing system based upon knowledge‐based renal dosing guideline was successfully developed and implemented into a local clinical practicesetting.
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특수대학원 > 임상약학대학원 > 1. Journal Articles

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