Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Alleviation of periodontal disease using Lactobacillus curvatus SMFM2016-NK

Authors
Choi, YukyungPark, EunyoungKim, SejeongHa, JimyeongOh, HyeminKim, YujinLee, YewonSeo, YeongeunKang, JoohyunLee, SoominLee, HeeyoungYoon, YohanChoi, Kyoung-Hee
Issue Date
Aug-2021
Publisher
ELSEVIER
Keywords
Probiotics; Periodontitis; Whole genome sequencing; Next generation sequencing; Microbiome; Safety
Citation
JOURNAL OF FUNCTIONAL FOODS, v.83, pp 1 - 13
Pages
13
Journal Title
JOURNAL OF FUNCTIONAL FOODS
Volume
83
Start Page
1
End Page
13
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/146494
DOI
10.1016/j.jff.2021.104531
ISSN
1756-4646
2214-9414
Abstract
The effects of Lactobacillus curvatus SMFM2016-NK on periodontal disease and its actions in the intestines were examined, and the genome sequence of L. curvatus SMFM2016-NK was determined. A total of 110 probiotic bacteria isolated from cheese and 360 isolated from kimchi were examined in this study. Isolates 4Y, 44, and 98-1-3 were found to display antimicrobial effects. In particular, isolate 98-1-3 decreased volume loss in trabecular tissues, alleviated the histological score and alveolar process volume, decreased the number of osteoclast cells, and increased the number of osteoblast cells. Periodontitis and treatment with isolate 98-1-3 were found to alter the composition of gut microbiome. Isolate 98-1-3 was eventually named L. curvatus SMFM2016-NK, and its genome sequence was determined. Based on the lack of beta-glucuronidase activity, antibiotic resistance, and biogenic amines, L. curvatus SMFM2016-NK was deemed safe. Our findings suggest that L. curvatus SMFM2016-NK is both a novel strain and a beneficial probiotic for alleviating symptoms of periodontal disease.
Files in This Item
There are no files associated with this item.
Appears in
Collections
생활과학대학 > 식품영양학과 > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Yoon, Yo Han photo

Yoon, Yo Han
생활과학대학 (식품영양학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE