Off-label antipsychotic use patterns among Texas Medicaid adults 2013-2016
- Authors
- Chen, Shuang; Barner, Jamie C.; Cho, Eun
- Issue Date
- Jul-2021
- Publisher
- FUTURE MEDICINE LTD
- Keywords
- antipsychotic agents; Medicaid; off-label use; prevalence; retrospective studies; treatment trends
- Citation
- JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH, v.10, no.14, pp 1045 - 1053
- Pages
- 9
- Journal Title
- JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH
- Volume
- 10
- Number
- 14
- Start Page
- 1045
- End Page
- 1053
- URI
- https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/146522
- DOI
- 10.2217/cer-2021-0048
- ISSN
- 2042-6305
2042-6313
- Abstract
- Aim: To describe trends in off-label antipsychotic use among Texas Medicaid adults and examine whether demographic and clinical characteristics were associated with off-label use. Methods: Three diagnostic groups (i.e. no diagnosis, on label and off-label) were created based on mental health disorder diagnoses and related antipsychotic prescriptions. Results: During 2013-2016, the prevalence of off-label antipsychotic use decreased from 22.5% to 17.4% and the proportions of no mental health diagnosis remained stable (7.3-9.4%). Patients aged >= 25 years and second-generation antipsychotic users had significantly lower odds of receiving antipsychotics off-label or with no diagnosis. Conclusion: Compared with previous Medicaid database studies, the proportions of off-label antipsychotic use and antipsychotic use with no concurrent psychiatric diagnosis were notably lower.
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