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Off-label antipsychotic use patterns among Texas Medicaid adults 2013-2016

Authors
Chen, ShuangBarner, Jamie C.Cho, Eun
Issue Date
Jul-2021
Publisher
FUTURE MEDICINE LTD
Keywords
antipsychotic agents; Medicaid; off-label use; prevalence; retrospective studies; treatment trends
Citation
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH, v.10, no.14, pp 1045 - 1053
Pages
9
Journal Title
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH
Volume
10
Number
14
Start Page
1045
End Page
1053
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/146522
DOI
10.2217/cer-2021-0048
ISSN
2042-6305
2042-6313
Abstract
Aim: To describe trends in off-label antipsychotic use among Texas Medicaid adults and examine whether demographic and clinical characteristics were associated with off-label use. Methods: Three diagnostic groups (i.e. no diagnosis, on label and off-label) were created based on mental health disorder diagnoses and related antipsychotic prescriptions. Results: During 2013-2016, the prevalence of off-label antipsychotic use decreased from 22.5% to 17.4% and the proportions of no mental health diagnosis remained stable (7.3-9.4%). Patients aged >= 25 years and second-generation antipsychotic users had significantly lower odds of receiving antipsychotics off-label or with no diagnosis. Conclusion: Compared with previous Medicaid database studies, the proportions of off-label antipsychotic use and antipsychotic use with no concurrent psychiatric diagnosis were notably lower.
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