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울금 검 제제가 알코올의 혈중농도와 숙취에 미치는 영향Effects of Curcuma long gum preparation on the Blood Alcohol Level and Hangover

Other Titles
Effects of Curcuma long gum preparation on the Blood Alcohol Level and Hangover
Authors
곡리영남윤성조성인임성혁정주철방준석손의동김진만김민수구교환정지훈
Issue Date
Jun-2010
Publisher
한국임상약학회
Citation
한국임상약학회지, v.20, no.1, pp.1 - 8
Journal Title
한국임상약학회지
Volume
20
Number
1
Start Page
1
End Page
8
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/147909
ISSN
1226-6051
Abstract
We conducted a single blind, randomized and crossover clinical trial in order to test the effect of curcuma longa herbal mixture on blood alcohol level and alcohol hangover in 19 healthy volunteers. The herbal mixture did not show a statistical significance in Cmax, Tmax and AUC in alcohol disposition. The herbal mixture did not also ameliorate blood laboratory result after alcohol consumption. In contrast, the herbal mixture is shown effective on alcohol hangover. In behavior tests, the fewer subjects in the herbal mixture group were impaired with alcohol than in reference group. Moreover, the symptom severity score in the herbal mixture was lower than that in reference group. The symptom severity score was statistically especially in stomach pain, diarrhea, concentration disorder, memory and bad breath at drinking day and one day after drinking. These results indicate that the general symptoms seemed to be recovered as time goes on. From these results, it was suggested that the herbal mixture have a beneficial effect on modulating alcohol hangover.
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