Sources of Polycyclic Aromatic Hydrocarbon Exposure in Non-Occupationally Exposed Koreans
DC Field | Value | Language |
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dc.contributor.author | Yang M. | - |
dc.contributor.author | Kang D. | - |
dc.contributor.author | Choi Y. | - |
dc.contributor.author | Lee S.-M. | - |
dc.contributor.author | Kim S. | - |
dc.contributor.author | Lee E. | - |
dc.contributor.author | Cheong H.-K. | - |
dc.contributor.author | Chang S.-S. | - |
dc.contributor.author | Jang J.-Y. | - |
dc.date.accessioned | 2022-04-19T12:05:28Z | - |
dc.date.available | 2022-04-19T12:05:28Z | - |
dc.date.issued | 2003-01 | - |
dc.identifier.issn | 0893-6692 | - |
dc.identifier.issn | 1098-2280 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/149206 | - |
dc.description.abstract | Urinary 1-hydroxypyrene (1-OHP), an exposure biomarker for polycyclic aromatic hydrocarbons (PAHs), was used to identify potential sources of PAH exposure for 660 Koreans who were not occupationally exposed to PAHs (65% male; 35% female; mean age, 36.5 ± 11.1 years). In this study, 74% of subjects had detectable levels of urinary 1-OHP, with a concentration range of 0.001-3.796 μg/L (median, 0.079 μg/L). A backward elimination was conducted: five variables were selected with a significance level for removal of P ≤ 0.1. The results of this study showed that residence in areas with relatively poor environmental conditions (Seoul and Suwon) was strongly associated with high concentrations of urinary 1-OHP (P = 0.007), while consumption of fried chicken and length of time spent outdoors had marginal positive associations with urinary 1-OHP levels (P = 0.06 and P = 0.09, respectively). Compared with the above three factors, tobacco smoking and urinary cotinine levels were poorly associated with urinary 1-OHP (P = 0.16 and 0.23, respectively). Pear consumption had an inverse association with urinary 1-OHP levels (P < 0.01). Individual variations in urinary 1-OHP concentrations were evaluated by considering the subjects' age, sex, and genetic polymorphisms in enzymes involved in the metabolism of PAHs. Among the indivi | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | John Wiley & Sons Inc. | - |
dc.title | Sources of Polycyclic Aromatic Hydrocarbon Exposure in Non-Occupationally Exposed Koreans | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1002/em.10196 | - |
dc.identifier.scopusid | 2-s2.0-0346728795 | - |
dc.identifier.wosid | 000187864100004 | - |
dc.identifier.bibliographicCitation | Environmental and Molecular Mutagenesis, v.42, no.4, pp 250 - 257 | - |
dc.citation.title | Environmental and Molecular Mutagenesis | - |
dc.citation.volume | 42 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 250 | - |
dc.citation.endPage | 257 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | 1-hydroxypyrene | - |
dc.subject.keywordAuthor | Biomarker | - |
dc.subject.keywordAuthor | Exposure route | - |
dc.subject.keywordAuthor | Genetic polymorphism | - |
dc.subject.keywordAuthor | Polycyclic aromatic hydrocarbons | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/em.10196 | - |
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