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Safety and efficacy of Korean red ginseng intervention (SAEKI) trial: rationale, design, and expected findings

Sievenpiper John LBuono Marco DiStavro P. MarkJenkins Alexandra LNam Ki YeulChoi MelodyNaeem AsimaLeiter Lawrence ASung Mi-KyungVuksan Vladimir
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Proceedings of the Ginseng society Conference (고려인삼학회:학술대회논문집), pp 424 - 455
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Proceedings of the Ginseng society Conference (고려인삼학회:학술대회논문집)
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Diabetes mellitus is reaching epidemic proportions worldwide. The insufficiency of medication to cope with this burden has coincided with a dramatic rise in the prevalence of use of complementary and alternative therapies, especially herbal treatments. This surge in demand presents a challenge to prove the safety and efficacy of these treatments in diabetes. Korean red ginseng (steam treated Panax ginseng C.A. Meyer) is a strong candidate to succeed. It has been shown to possess a multitude of hypoglycemic effects and improve metabolic disturbances related to diabetes in in vitro and animal models. Data in humans is also emerging to support these benefits. Whether these results can be replicated in a rigorous clinical testing program is unclear. We therefore investigated the antidiabetic effects of Korean red ginseng in a series of 2 acute and 1 longterm randomized, double-blinded, placebo-controlled clinical trials. This paper provides the rationale for this program of study, expanding on the problem of diabetes, its management, and the possible role for Korean red ginseng. It then describes the design and expected findings.
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생활과학대학 > 식품영양학과 > 1. Journal Articles


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생활과학대학 (식품영양학과)
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