Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Versatile naphthalimides: Their optical and biological behavior and applications from sensing to therapeutic purposes

Authors
Gopala, L.Cha, Y.Lee, M.H.
Issue Date
May-2022
Publisher
Elsevier Ltd
Keywords
Anticancer agent; Bio-imaging; Chemical sensors; Diagnosis; Naphthalimide; Photosensitizer
Citation
Dyes and Pigments, v.201, pp.1 - 15
Journal Title
Dyes and Pigments
Volume
201
Start Page
1
End Page
15
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/151314
DOI
10.1016/j.dyepig.2022.110195
ISSN
0143-7208
Abstract
Naphthalimides and their derivatives have been extensively studied in various research fields such as supramolecular chemistry, sensor materials, and pharmaceutical chemistry, due to their ease of synthesis, the potential to tune their optical properties and biological activity. In this review, we highlight recent advances in the development of versatile naphthalimides as chemical sensors for metal ions, anions, reactive oxygen species, and cancer-associated enzymes, therapeutic agents, and photosensitizers, and described their optical response and sensing mechanisms, bioactivity and associated molecular docking studies, photosensitivity for photodynamic therapy and related density functional theory (DFT) calculations. Rational design concepts related to the chemical structure of naphthalimides in various applications ranging from sensing to therapeutic purposes are described. Additionally, this review demonstrates the behavior of these naphthalimides with a variety of analytical methods such as absorption and fluorescence spectroscopy, nuclear magnetic resonance and mass analyses, fluorescence confocal microscopic studies, molecular dynamics simulation, DTF calculation, molecular docking studies, and antiproliferative experiments in vitro and in vivo. We hope that this review will help in the future advances of versatile naphthalimides and in the design of optical and biological validation studies. Prospects for future research directions are provided by highlighting the optical and biological benefits of naphthalimides. © 2022 Elsevier Ltd
Files in This Item
There are no files associated with this item.
Appears in
Collections
이과대학 > 화학과 > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Lee, Min Hee photo

Lee, Min Hee
이과대학 (화학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE