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Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots

Authors
Lee, YeonjaeChoi, JihoChoi, YoungeunPark, Sue MinYoon, ChangKyu
Issue Date
Jan-2023
Publisher
Journal of Visualized Experiments
Citation
Journal of Visualized Experiments, v.2023, no.191
Journal Title
Journal of Visualized Experiments
Volume
2023
Number
191
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/152110
DOI
10.3791/64870
ISSN
1940-087X
Abstract
The present protocol describes the creation of four-dimensional (4D), time-dependent, shape-changeable, stimuli-responsive soft robots using a three-dimensional (3D) bioprinting method. Recently, 4D printing techniques have been extensively proposed as innovative new methods for developing shape-transformable soft robots. In particular, 4D time-dependent shape transformation is an essential factor in soft robotics because it allows effective functions to occur at the right time and place when triggered by external cues, such as heat, pH, and light. In line with this perspective, stimuli-responsive materials, including hydrogels, polymers, and hybrids, can be printed to realize smart shape-transformable soft robotic systems. The current protocol can be used to fabricate thermally responsive soft grippers composed of N-isopropylacrylamide (NIPAM)-based hydrogels, with overall sizes ranging from millimeters to centimeters in length. It is expected that this study will provide new directions for realizing intelligent soft robotic systems for various applications in smart manipulators (e.g., grippers, actuators, and pick-and-place machines), healthcare systems (e.g., drug capsules, biopsy tools, and microsurgeries), and electronics (e.g., wearable sensors and fluidics). © 2023 JoVE Journal of Visualized Experiments.
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