다낭성난소증후군으로 인한 불임 여성에서 경구 배란유도제의 효능: 메타메타분석
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이지은 | - |
dc.contributor.author | 이소영 | - |
dc.contributor.author | 정은아 | - |
dc.contributor.author | 김미리 | - |
dc.contributor.author | 조은 | - |
dc.date.accessioned | 2023-12-28T06:30:21Z | - |
dc.date.available | 2023-12-28T06:30:21Z | - |
dc.date.issued | 2023-11 | - |
dc.identifier.issn | 2508-6596 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/159535 | - |
dc.description.abstract | Background: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. Clomiphene citrate (CC), letrozole (LE), metformin (M), and CC plus M (CCM) are available therapeutic options for PCOS-related infertility. Therefore, we conducted a meta-meta-analysis to provide summarized effect sizes for reproductive outcomes and to assist health providers in selecting appropriate ovulation induction agents (OIAs). Methods: This study used three databases to perform a meta-meta-analysis to evaluate the pooled estimates of ovulation rate (OR), live birth (LB), and pregnancy (P). Results: A total of 17 meta-analyses and 71 primary studies were included in this overview. There was a high overlap between primary studies, and the corrected covered area score was 10.12%. Compared to CC, LE significantly improved the OR per patient (RR 1.30, 95%CI 1.02-1.65), LB (RR 1.52, 95%CI 1.37-1.69), and P (RR 1.24, 95%CI 1.09-1.43). CCM resulted in a 1.30 times higher pregnancy rate than CC (95%CI 1.21-1.40). M was no more effective than CC in OR (RR 0.73, 95%CI 0.63-0.86) and LB (RR 0.85, 95%CI 0.75-0.97). Conclusion: Patients with PCOS-related infertility treated with LE have a higher chance of ovulation, live birth, and pregnancy than those treated with CC. CCM significantly increased the pregnancy rate compared to CC, and M monotherapy was not competitive with CC for reproductive outcomes. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국보건사회약료경영학회 | - |
dc.title | 다낭성난소증후군으로 인한 불임 여성에서 경구 배란유도제의 효능: 메타메타분석 | - |
dc.title.alternative | A Meta-Meta-Analysis: Effectiveness of Oral Ovulation Induction Agents for Infertile Women with Polycystic Ovary Syndrome | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.bibliographicCitation | 한국보건사회약료경영학회지, v.11, no.2, pp 88 - 97 | - |
dc.citation.title | 한국보건사회약료경영학회지 | - |
dc.citation.volume | 11 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 88 | - |
dc.citation.endPage | 97 | - |
dc.identifier.kciid | ART003025026 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | kciCandi | - |
dc.subject.keywordAuthor | meta-meta-analysis | - |
dc.subject.keywordAuthor | polycystic ovary syndrome | - |
dc.subject.keywordAuthor | infertility | - |
dc.subject.keywordAuthor | ovulation induction | - |
dc.identifier.url | http://www.kasmcp.or.kr/subList/32000002136 | - |
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