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마스크네 화장품이 휘발성 유기화합물(VOC)에 의해 유발된 염증에 미치는 효과Effects of Maskne Cosmetics to Inflammation Elicited by Volatile Organic Compounds (VOC)

Other Titles
Effects of Maskne Cosmetics to Inflammation Elicited by Volatile Organic Compounds (VOC)
Authors
김민정김민경김정희
Issue Date
Apr-2024
Publisher
한국미용학회
Keywords
Acne mechanica; Anti-immflammatory; Copper tripeptide-1; Humulus lupulus extract; Maskne cosmetic
Citation
한국미용학회지, v.30, no.2, pp 260 - 269
Pages
10
Journal Title
한국미용학회지
Volume
30
Number
2
Start Page
260
End Page
269
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/160018
DOI
10.52660/JKSC.2024.30.2.260
ISSN
1229-4349
Abstract
Wearing a mask is still advised since COVID-19 continues to spread. However, masks may also irritate the skin and cause mask acne, often known as “maskne”, which is a type of acne mechanica caused by friction between the skin and clothing. Therefore, there is a need to develop an effective maskne cosmetic. In this study, we made the maskne cosmetics containing Humulus lupulus extract and Copper tripeptide-1 and investigated its stability, safety and anti-inflammatory efficacy. The results indicated that the samples were stable after centrifugation, temperature cycling, viscosity, and pH tests. The cell viability range of maskne cosmetics was within 71%- 80% at 2.5 mg/mL, which presented a weak cytotoxicity. In addition, cosmetic safety test results revealed that maskne cosmetics containing humulus lupulus extract and copper tripeptide-1 did not cause any skin responses. Expression levels of IL-1β and IL-6 were lowest in HS68 cells after treatment with a lotion containing 3%humulus lupulus extract and 3% Copper tripeptide-1. It was confirmed that maskne cosmetics containing Humulus lupulus extract and Copper tripeptide-1 reduce the expression of inflammatory cytokines IL-1, and IL-6 caused by wearing a mask. These findings indicate that prepared lotion containing 3% Humulus lupulus extract and 3% Copper tripeptide-1 is a promising maskne cosmetic with commercial potential.
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