Gender differences in the levels of bisphenol A metabolites in urine
DC Field | Value | Language |
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dc.contributor.author | Kim, YH | - |
dc.contributor.author | Kim, CS | - |
dc.contributor.author | Park, S | - |
dc.contributor.author | Han, SY | - |
dc.contributor.author | Pyo, MY | - |
dc.contributor.author | Yang, MH | - |
dc.date.available | 2021-02-22T16:16:52Z | - |
dc.date.issued | 2003-12 | - |
dc.identifier.issn | 0006-291X | - |
dc.identifier.issn | 1090-2104 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/16137 | - |
dc.description.abstract | The metabolism of bisphenol A (BPA), a suspected endocrine disruptor, should be considered for monitoring human exposure to BPA, because the conjugation with beta-D-glucuronide and sulfate reduces the estrogenic activity. In this study, BPA levels in 30 healthy Koreans (men, N = 15, 42.6 +/- 2.4 years; women, N = 15, 43.0 +/- 2.7 years) were analyzed from urine treated with/without beta-glucuronidase and/or sulfatase by an RP-HPLC with fluorescence detection. The total BPA concentrations including free BPA and the urinary conjugates were similar in men and women (2.82 +/- 0.73 and 2.76 +/- 0.54 ng ml(-1), respectively), but gender differences were found in the levels of urinary BPA conjugates. Men had significantly higher levels of BPA-glucuronide (2.34 +/- 0.85 ng ml-1) than women (1.00 +/- 0.34 ng ml(-1)), whereas women had higher levels of BPA-sulfate (1.20 +/- 0.32 ng ml(-1)) than men (0.49 +/- 0.27 ng ml(-1)). (C) 2003 Elsevier Inc. All rights reserved. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ACADEMIC PRESS INC ELSEVIER SCIENCE | - |
dc.title | Gender differences in the levels of bisphenol A metabolites in urine | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1016/j.bbrc.2003.10.135 | - |
dc.identifier.scopusid | 2-s2.0-0345276457 | - |
dc.identifier.wosid | 000186987000026 | - |
dc.identifier.bibliographicCitation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.312, no.2, pp 441 - 448 | - |
dc.citation.title | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - |
dc.citation.volume | 312 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 441 | - |
dc.citation.endPage | 448 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.subject.keywordPlus | ENDOCRINE DISRUPTORS | - |
dc.subject.keywordPlus | RAT | - |
dc.subject.keywordPlus | CHEMICALS | - |
dc.subject.keywordPlus | HEALTH | - |
dc.subject.keywordAuthor | bisphenol A | - |
dc.subject.keywordAuthor | endocrine disruptor | - |
dc.subject.keywordAuthor | beta-glueuronidase | - |
dc.subject.keywordAuthor | sulfatase | - |
dc.subject.keywordAuthor | urinary conjugates | - |
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