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Synthesis and antiviral activity of novel C-methyl branched cyclopropyl nucleosides

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dc.contributor.authorKwak, EY-
dc.contributor.authorHong, JH-
dc.contributor.authorPark, Y-
dc.contributor.authorChoi, BG-
dc.date.available2021-02-22T16:17:18Z-
dc.date.created2020-09-01-
dc.date.issued2003-09-
dc.identifier.issn0253-6269-
dc.identifier.urihttps://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/16170-
dc.description.abstractA series of novel cyclopropyl nucleosides was synthesized using the highly stereoselective Simmons-Smith reaction starting from 1,2:5,6-di-O-isopropylidene-D-mannitol. The structural assignments of these nucleosides were determined by NMR studies and X-ray crystallography. All the synthesized nucleosides were assayed against several viruses.-
dc.language영어-
dc.language.isoen-
dc.publisherPHARMACEUTICAL SOCIETY KOREA-
dc.subjectHUMAN-IMMUNODEFICIENCY-VIRUS-
dc.subjectHEPATITIS-B VIRUS-
dc.subjectBIOLOGICAL EVALUATION-
dc.subjectANALOGS-
dc.subjectPOTENT-
dc.subjectHIV-
dc.titleSynthesis and antiviral activity of novel C-methyl branched cyclopropyl nucleosides-
dc.typeArticle-
dc.contributor.affiliatedAuthorPark, Y-
dc.identifier.doi10.1007/BF02976674-
dc.identifier.scopusid2-s2.0-30444434575-
dc.identifier.wosid000185668900002-
dc.identifier.bibliographicCitationARCHIVES OF PHARMACAL RESEARCH, v.26, no.9, pp.679 - 685-
dc.relation.isPartOfARCHIVES OF PHARMACAL RESEARCH-
dc.citation.titleARCHIVES OF PHARMACAL RESEARCH-
dc.citation.volume26-
dc.citation.number9-
dc.citation.startPage679-
dc.citation.endPage685-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.subject.keywordPlusHUMAN-IMMUNODEFICIENCY-VIRUS-
dc.subject.keywordPlusHEPATITIS-B VIRUS-
dc.subject.keywordPlusBIOLOGICAL EVALUATION-
dc.subject.keywordPlusANALOGS-
dc.subject.keywordPlusPOTENT-
dc.subject.keywordPlusHIV-
dc.subject.keywordAuthorcyclopropyl nucleoside-
dc.subject.keywordAuthorantiviral agent-
dc.subject.keywordAuthorSimmons-Smith cyclopropanation-
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