Synthesis and molecular structure of tetrahomodioxa p-phenylcalix[4] arene tetra ester derivative in 1,4-alternate conformation

Abstract

Reaction of tetrahomodioxa p-phenylcalix[4]arene with ethyl bromoacetate and potassium carbonate in acetone leads to the title tetra ester derivative, 7,13,21,27-tetra-phenyl-29,30, 31,32-tetrakis(ethoxycarbonyl)methoxy-2,3,16,17-tetrahomo-3,17-dioxacalix[4] arene, its structure was determined by NMR spectra as 1,4-alternate conformation. The molecular structure has been solved by X-ray diffraction methods. The molecule has: a conformation with pseudo center of symmetry. The benzene ring A is up, ring C is down, B and D rings are flat with respect to the plane of the macrocyclic ring.