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Structure-activity relationships of APIO nucleosides as potential antiviral agents
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Jeong, LS | - |
| dc.contributor.author | Moon, HR | - |
| dc.contributor.author | Hong, JH | - |
| dc.contributor.author | Yoo, SJ | - |
| dc.contributor.author | Choi, WJ | - |
| dc.contributor.author | Kim, HO | - |
| dc.contributor.author | Ahn, HS | - |
| dc.contributor.author | Baek, HW | - |
| dc.contributor.author | Chun, MW | - |
| dc.contributor.author | Kim, HD | - |
| dc.contributor.author | Kim, J | - |
| dc.contributor.author | Choi, JR | - |
| dc.date.available | 2021-03-12T00:40:09Z | - |
| dc.date.issued | 2001-04 | - |
| dc.identifier.issn | 1525-7770 | - |
| dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/17438 | - |
| dc.description.abstract | Several types of novel apio nucleosides were synthesized starting from 1,3-dihydroxyacetone and evaluated for antiviral activity. Among compounds tested, amino substituted apio dideoxynucleosides exhibited anti-HBV activity, while thioapio dideoxynucleosides were found to be active against HIV-1. Apio dideoxydidehydro nucleosides showed moderate to potent anti-HCMV activity, but their bioisosteric thioapio dideoxydidehydro nucleosides did not exhibit any significant antiviral activity. | - |
| dc.format.extent | 4 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | MARCEL DEKKER INC | - |
| dc.title | Structure-activity relationships of APIO nucleosides as potential antiviral agents | - |
| dc.type | Article | - |
| dc.publisher.location | 미국 | - |
| dc.identifier.doi | 10.1081/NCN-100002344 | - |
| dc.identifier.scopusid | 2-s2.0-0034839590 | - |
| dc.identifier.wosid | 000170690500047 | - |
| dc.identifier.bibliographicCitation | NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, v.20, no.4-7, pp 657 - 660 | - |
| dc.citation.title | NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | - |
| dc.citation.volume | 20 | - |
| dc.citation.number | 4-7 | - |
| dc.citation.startPage | 657 | - |
| dc.citation.endPage | 660 | - |
| dc.type.docType | Article; Proceedings Paper | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
| dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
| dc.subject.keywordPlus | ISOMERIC DIDEOXYNUCLEOSIDES | - |
| dc.identifier.url | https://www.tandfonline.com/doi/abs/10.1081/NCN-100002344 | - |
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