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Synthesis of halogenated 9-(dihydroxycyclopent-4 '-enyl) adenines and their inhibitory activities against S-adenosylhomocysteine hydrolase
- Authors
- Jeong, LS; Park, JG; Choi, WJ; Moon, HR; Lee, KM; Kim, HO; Kim, HD; Chun, MW; Park, HY; Kim, K; Sheen, YY
- Issue Date
- Oct-2003
- Publisher
- MARCEL DEKKER INC
- Keywords
- S-adenosylhomocysteine hydrolase; halogenated 9-(dihydroxycyclopent-4 '-enyl); adenines '
- Citation
- NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, v.22, no.5-8, pp 919 - 921
- Pages
- 3
- Journal Title
- NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Volume
- 22
- Number
- 5-8
- Start Page
- 919
- End Page
- 921
- ISSN
- 1525-7770
- Abstract
- Novel halovinyl analogues of neplanocin A without 4'-hydroxymethyl group were easily synthesized starting from D-ribose via cyclopentenone 5 as a key intermediate and their inhibitory activity against SAH hydrolase was assayed.
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