Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Inhibition of Nitric Oxide Synthesis by 8-epi-xanthatin in Activated RAW 264.7 Cells활성화한 RAW 264.7 세포주에서 8-epi-xanthatin의 Nitric Oxide 생성저해

Other Titles
활성화한 RAW 264.7 세포주에서 8-epi-xanthatin의 Nitric Oxide 생성저해
Authors
이화진정연수류시용류재하
Issue Date
Oct-1998
Publisher
대한약학회
Citation
약 학 회 지, v.42, no.5, pp.540 - 543
Journal Title
약 학 회 지
Volume
42
Number
5
Start Page
540
End Page
543
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/17535
ISSN
0377-9556
Abstract
The nitric oxide (NO) produced in large amounts by inducible nitric oxide synthase is known to be responsible for the vasodilation and hypotension observed in septic shock. We have found that 8-epi-xanthatin from Xanthium strumarium L. inhibited the production of NO in LPS-activated RAW 264.7 cells ($IC_{50}$ value was 1.5 ${\mu}$M). This activity was resulted from the suppressing of inducible nitric oxide synthase enzyme expression.
Files in This Item
Go to Link
Appears in
Collections
약학대학 > 약학부 > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Ryu, Jae Ha photo

Ryu, Jae Ha
약학대학 (약학부)
Read more

Altmetrics

Total Views & Downloads

BROWSE