Interplay Between Primary Cilia and Autophagy and Its Controversial Roles in Cancer
- Authors
- Ko, Je Yeong; Lee, Eun Ji; Park, Jong Hoon
- Issue Date
- Jul-2019
- Publisher
- KOREAN SOC APPLIED PHARMACOLOGY
- Keywords
- Cilia; Autophagy; Ciliopathy; Cancer
- Citation
- BIOMOLECULES & THERAPEUTICS, v.27, no.4, pp 337 - 341
- Pages
- 5
- Journal Title
- BIOMOLECULES & THERAPEUTICS
- Volume
- 27
- Number
- 4
- Start Page
- 337
- End Page
- 341
- URI
- https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/2944
- DOI
- 10.4062/biomolther.2019.056
- ISSN
- 1976-9148
2005-4483
- Abstract
- Primary cilia and autophagy are two distinct nutrient-sensing machineries required for maintaining intracellular energy homeostasis, either via signal transduction or recycling of macromolecules from cargo breakdown, respectively. Potential correlations between primary cilia and autophagy have been recently suggested and their relationship may increase our understanding of the pathogenesis of human diseases, including ciliopathies and cancer. In this review, we cover the current issues concerning the bidirectional interaction between primary cilia and autophagy and discuss its role in cancer with cilia defect.
- Files in This Item
-
Go to Link
- Appears in
Collections - 이과대학 > 생명시스템학부 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.