Detailed Information

Cited 0 time in webofscience Cited 2 time in scopus
Metadata Downloads

Weight change and risk of uterine leiomyomas: Korea Nurses' Health Study

Authors
Lee, Ji-EunSong, SihanCho, EunyoungJang, Hee JungJung, HeejaLee, Hea-YoungKim, SueKim, OksooLee, Jung Eun
Issue Date
Nov-2018
Publisher
TAYLOR & FRANCIS LTD
Keywords
Body mass index; weight change; body size; uterine leiomyoma; Korea nurses' health study
Citation
CURRENT MEDICAL RESEARCH AND OPINION, v.34, no.11, pp.1913 - 1919
Journal Title
CURRENT MEDICAL RESEARCH AND OPINION
Volume
34
Number
11
Start Page
1913
End Page
1919
URI
https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/4203
DOI
10.1080/03007995.2018.1462783
ISSN
0300-7995
Abstract
Objective: This study examined the associations between anthropometric measures and uterine leiomyomas. Methods: This study included a total of 5,062 women (median age of 35.5 years) who had experienced pregnancy and, of these women, 210 reported a diagnosis of uterine leiomyomas within the past 2 years prior to baseline in the Korea Nurses' Health Study. Participants were asked about their anthropometric factors. The odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated using logistic regression models. Results: Mean body mass index (BMI) was 21.8 kg/m(2) among non-cases. An increase in weight from the age of 18 years to the present was associated with increased risk of uterine leiomyomas (p for trend = .002); compared to women whose weight remained stable, the multivariate ORs (95% CIs) were 1.84 (1.22-2.76) for weight gain of 5-10 kg and 2.00 (1.25-3.20) for weight gain of more than 10 kg since age 18. A similar pattern was observed when the analysis was limited to women with a BMI of 18.5-25 kg/m(2). Current weight was associated with higher odds of uterine leiomyomas. No associations were found for body size in childhood or in adolescence, weight at age 18, current BMI, or current body size. Conclusions: Weight gain in adulthood was associated with increased risk of uterine leiomyomas in Korean women, even in those with normal weight.
Files in This Item
There are no files associated with this item.
Appears in
Collections
생활과학대학 > 식품영양학과 > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Altmetrics

Total Views & Downloads

BROWSE