Anti-angiogenic, Anti-inflammatory and Anti-nociceptive Activities of Vanillyl Alcohol
- Authors
- Jung, Hynn-Joo; Song, Yun Seon; Lim, Chang-Jin; Park, Eun-Hee
- Issue Date
- Oct-2008
- Publisher
- PHARMACEUTICAL SOC KOREA
- Keywords
- Vanillyl alcohol; Anti-inflammatory; Anti-angiogenic; Anti-nociceptive
- Citation
- ARCHIVES OF PHARMACAL RESEARCH, v.31, no.10, pp 1275 - 1279
- Pages
- 5
- Journal Title
- ARCHIVES OF PHARMACAL RESEARCH
- Volume
- 31
- Number
- 10
- Start Page
- 1275
- End Page
- 1279
- URI
- https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/7824
- DOI
- 10.1007/s12272-001-2106-1
- ISSN
- 0253-6269
1976-3786
- Abstract
- Vanillyl alcohol displayed a significant inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. Vanillyl alcohol was also shown to contain anti-inflammatory activity using acetic acid-induced permeability and carrageenan-induced air pouch models in mice. Anti-nociceptive activity of vanillyl alcohol was also assessed using acetic acid-induced writhing test in mice. Taken together, vanillyl alcohol possesses anti-angiogenic, anti-inflammatory, and anti-nociceptive activities, which may be partly responsible for pharmacological efficacies of several folkloric medicines containing vanillyl alcohol.
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