To quit or not: Vulnerability of women to smoking tobacco
- Authors
- Park, Se-Jung; Yi, Bitna; Lee, Ho-Sun; Oh, Woo-Yeon; Na, Hyun-Kyung; Lee, Minjeong; Yang, Mihi
- Issue Date
- Jan-2016
- Publisher
- TAYLOR & FRANCIS INC
- Keywords
- Tobacco smoking; women; genetic polymorphisms; nicotine; epigenetics
- Citation
- JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS, v.34, no.1, pp 33 - 56
- Pages
- 24
- Journal Title
- JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS
- Volume
- 34
- Number
- 1
- Start Page
- 33
- End Page
- 56
- URI
- https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/9978
- DOI
- 10.1080/10590501.2015.1131539
- ISSN
- 1059-0501
1532-4095
- Abstract
- Tobacco smoking is currently on the rise among women, and can pose a greater health risk. In order to understand the nature of the increase in smoking prevalence among women, we focused on the vulnerability of women to smoking behaviors-smoking cessation or tobacco addiction-and performed a systematic review of the socioeconomic and intrinsic factors as well as tobacco ingredients that affect women's susceptibility to smoking tobacco. We observed that nicotine and other tobacco components including cocoa-relatives, licorice products, and menthol aggravate tobacco addiction in women rather than in men. Various genetic and epigenetic alterations in dopamine pathway and the pharmaco-kinetics and -dynamic factors of nicotine also showed potential evidences for high susceptibility to tobacco addiction in women. Therefore, we suggest systemic approaches to prevent tobacco smoking-related health risks, considering gene-environment-gender interaction.
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