Evaluation of the Antiangiogenic, Anti-inflammatory, and Antinociceptive Activities of Morin
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초록

Morin displayed significant inhibition of chick chorioallantoic membrane (CAM) angiogenesis and was able to increase the endostatin level in human umbilical vein endothelial cells (HUVECs). Morin was shown to contain an in vivo anti-inflammatory activity using a carrageenan-induced air pouch model in mice. Antinociceptive activity of morin was also assessed using an acetic acid-induced writhing test in mice. Collectively, morin possesses antiangiogenic, in vivo anti-inflammatory, and antinociceptive activities.

키워드

morinantiangiogenicanti-inflammatoryantinociceptiveendostatinCANCERCELLSRATSANGIOGENESISANTIOXIDANTACTIVATIONAPOPTOSISFLAVONOLCOLITISTARGETS
제목
Evaluation of the Antiangiogenic, Anti-inflammatory, and Antinociceptive Activities of Morin
저자
Jung, Hyun-JooKim, Su-JungSong, Yun-SeonPark, Eun-HeeLim, Chang-Jin
DOI
10.1055/s-0029-1186079
발행일
2010-02
유형
Article
저널명
Planta Medica
76
3
페이지
273 ~ 275