상세 보기
초록
The hydrazone-based Gd3+-texaphyrin doxorubicin conjugate 1, releases active doxorubicin at acidic pH values, allowing its components to be followed by two complementary imaging methods, namely Off-On fluorescence enhancement and MR imaging. It thus acts as a promising theranostic agent.
키워드
ANTICANCER DRUG-DELIVERY; GADOLINIUM(III) TEXAPHYRIN; MOTEXAFIN GADOLINIUM; RADIATION SENSITIZER; CANCER; PRODRUG; MECHANISMS; EFFICACY; REDUCTION; THERAPY
- 제목
- Acid-triggered release of doxorubicin from a hydrazone-linked Gd3+-texaphyrin conjugate
- 저자
- Lee, Min Hee; Kim, Eun-Joong; Lee, Hyunseung; Park, Sun Young; Hong, Kwan Soo; Kim, Jong Seung; Sessler, Jonathan L.
- 발행일
- 2016-09
- 유형
- Article
- 권
- 52
- 호
- 69
- 페이지
- 10551 ~ 10554