QUIRKY regulates root epidermal cell patterning through stabilizing SCRAMBLED to control CAPRICE movement in Arabidopsis
Citations

WEB OF SCIENCE

28
Citations

SCOPUS

32

초록

SCM, a leucine-rich repeat receptor-like kinase, is required for root epidermal cells to appropriately interpret their location and generate the proper cell-type pattern during Arabidopsis root development. Here, via a screen for scm-like mutants we describe a new allele of the QKY gene. We find that QKY is required for the appropriate spatial expression of several epidermal cell fate regulators in a similar manner as SCM in roots, and that QKY and SCM are necessary for the efficient movement of CPC between epidermal cells. We also show that turnover of SCM is mediated by a vacuolar degradation pathway triggered by ubiquitination, and that QKY prevents this SCM ubiquitination through their physical interaction. These results suggest that QKY stabilizes SCM through interaction, and this complex facilitates CPC movement between the epidermal cells to help establish the cell-type pattern in the Arabidopsis root epidermis.

키워드

RECEPTOR-LIKE KINASELATERAL INHIBITIONMEMBRANE-PROTEINSHAIR DEVELOPMENTFATEGENEPOSITIONSTRUBBELIGWEREWOLFPATHWAYS
제목
QUIRKY regulates root epidermal cell patterning through stabilizing SCRAMBLED to control CAPRICE movement in Arabidopsis
저자
Song, Jae HyoKwak, Su-HwanNam, Kyoung HeeSchiefelbein, JohnLee, Myeong Min
DOI
10.1038/s41467-019-09715-8
발행일
2019-04
유형
Article
저널명
Nature Communications
10