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초록
Hydrazide-linked naphthalimides undergo copper ion-selective hydrolysis with concomitant ratiometric fluorescence change. In addition, probe 1 is biocompatible and mainly localized to the endoplasmic reticulum ( ER) in live HeLa cells. It thus can be used for imaging copper accumulation in the ER of live cells, as implied in copper-overloaded situations.
키워드
WILSON DISEASE; CELLS; GLUTATHIONE; STRESS; SENSOR; GENE
- 제목
- An endoplasmic reticulum-selective ratiometric fluorescent probe for imaging a copper pool
- 저자
- Park, Sun Young; Kim, Woori; Park, Sun-Hee; Han, Jinhyoung; Lee, Jinju; Kang, Chulhun; Lee, Min Hee
- 발행일
- 2017-04
- 유형
- Article
- 권
- 53
- 호
- 32
- 페이지
- 4457 ~ 4460