상세 보기
- Sung, Nak-Yun;
- Choi, Jong-il;
- Yoon, Yohan;
- Lee, Soo-Young;
- Byun, Myung-Woo;
- 외 4명
WEB OF SCIENCE
4SCOPUS
4초록
This study evaluated the anti-allergic effect of low molecular weight beta-glucan (25 kDa) degraded by lambda-irradiation. Allergy was induced in mouse models administrated with lambda-irradiated low molecular weight and non-irradiated high molecular weight beta-glucan, respectively, for 7 days. However, only the mice treated with low molecular weight beta-glucan had a significantly decreased the total serum IgE and ovalbumin specific-IgE levels, and significantly increased Th 1 cytokine expression compared to only allergy induced mice. The allergic responses could be reduced by low molecular weight beta-glucan treated lambda-irradiation through the increased expression of Th 1 response and decreased expression of total IgE and antigen specific IgE.
키워드
- 제목
- Anti-allergic effect of low molecular weight beta-glucan prepared by lambda-irradiation
- 저자
- Sung, Nak-Yun; Choi, Jong-il; Yoon, Yohan; Lee, Soo-Young; Byun, Myung-Woo; Hwang, Yeoung-Jung; Koenari, Zubaidah Irawati; Lee, Ju-Woon; Kim, Jae-Hun
- 발행일
- 2011-06
- 유형
- Article
- 권
- 20
- 호
- 3
- 페이지
- 841 ~ 844