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초록
Chaga mushroom (Inonotus obliquus) has been identified to have various biological activities. This study was performed to investigate the potential of chaga mushroom as a immunomodulating functional food. When mouse splenocytes were exposed to various concentration of hot water extracts of chaga mushroom (IOE) with mitogens (Con A, LPS), splenocytes proliferation was significantly increased. Also, IFN-γ and IL-4 levels were significantly enhanced. Therefore, our results suggest that chaga mushroom may have the potential of being an immunomodulating functional food.
키워드
Chaga mushroom; Con A; LPS; IFN-γ; IL-4
- 제목
- 차가버섯 열수 추출물이 비장세포 증식능과 Cytokine 생성능에 미치는 영향
- 제목 (타언어)
- Effects of Hot Water Extract of Chaga Mushroom on the Proliferation and Cytokines Production of Mouse Splenocytes In Vitro
- 저자
- 김보라; 고숙경; 표명윤
- 발행일
- 2010-06
- 저널명
- 약 학 회 지
- 권
- 54
- 호
- 3
- 페이지
- 187 ~ 191