상세 보기
초록
We developed a fluorescent pH probe (1) capable of two-photon excitation and far-visible-emission based on FRET, composed of naphthalimide-piperazine-rhodamine. It exhibited a pH-dependent reversible and fast ratiometric fluorescence change in the rhodamine emission. Probe 1 was applied to image the pH perturbations of mitochondria in living cells and tissues.
키워드
RATIOMETRIC DETECTION; LIVING CELLS; PROBES
- 제목
- High-depth fluorescence imaging using a two-photon FRET system for mitochondrial pH in live cells and tissues
- 저자
- Chang, Min Jung; Kim, Kyutae; Park, Kyun Seob; Kang, Ji Su; Lim, Chang Su; Kim, Hwan Myung; Kang, Chulhun; Lee, Min Hee
- 발행일
- 2018-12
- 유형
- Article
- 권
- 54
- 호
- 96
- 페이지
- 13531 ~ 13534