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초록
We developed a fluorescent pH probe (1) capable of two-photon excitation and far-visible-emission based on FRET, composed of naphthalimide-piperazine-rhodamine. It exhibited a pH-dependent reversible and fast ratiometric fluorescence change in the rhodamine emission. Probe 1 was applied to image the pH perturbations of mitochondria in living cells and tissues.
키워드
RATIOMETRIC DETECTION; LIVING CELLS; PROBES
- 제목
- High-depth fluorescence imaging using a two-photon FRET system for mitochondrial pH in live cells and tissues
- 저자
- Chang, Min Jung; Kim, Kyutae; Park, Kyun Seob; Kang, Ji Su; Lim, Chang Su; Kim, Hwan Myung; Kang, Chulhun; Lee, Min Hee
- 발행일
- 2018-12
- 유형
- Article
- 권
- 54
- 호
- 96
- 페이지
- 13531 ~ 13534
- 언어
- ENG
- 출판사
- ROYAL SOC CHEMISTRY
- 발행국가
- 영국
- 분량
- 4 페이지
- ISSN
- E 1364-548X
P 1359-7345