Emerging Phospholipid Nanobiomaterials for Biomedical Applications to Lab-on-a-Chip, Drug Delivery, and Cellular Engineering
  • Rahimnejad, Maedeh
  • Rabiee, Navid
  • Ahmadi, Sepideh
  • Jahangiri, Sepideh
  • Sajadi, S. Mohammad
  • ... Kwon, Woosung
  • 외 4명
Citations

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Citations

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28

초록

The design of advanced nanobiomaterials to improve analytical accuracy and therapeutic efficacy has become an important prerequisite for the development of innovative nanomedicines. Recently, phospholipid nanobiomaterials including 2-methacryloylox-yethyl phosphorylcholine (MPC) have attracted great attention with remarkable characteristics such as resistance to nonspecific protein adsorption and cell adhesion for various biomedical applications. Despite many recent reports, there is a lack of comprehensive review on the phospholipid nanobiomaterials from synthesis to diagnostic and therapeutic applications. Here, we review the synthesis and characterization of phospholipid nanobiomaterials focusing on MPC polymers and highlight their attractive potentials for applications in micro/nanofabricated fluidic devices, biosensors, lab-on-a-chip, drug delivery systems (DDSs), COVID-19 potential usages for early diagnosis and even treatment, and artificial extracellular matrix scaffolds for cellular engineering.

키워드

nanobiomaterialsphospholipidlab-on-a-chipdrug deliverycellular engineeringBLOCK-COPOLYMER MICELLESMESSENGER-RNA VACCINES2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINESURFACE MODIFICATIONPROTEIN-ADSORPTIONPOLYMER HYDROGELTARGETED THERAPYPLASMA-MEMBRANEGRAPHENE OXIDECO-DELIVERY
제목
Emerging Phospholipid Nanobiomaterials for Biomedical Applications to Lab-on-a-Chip, Drug Delivery, and Cellular Engineering
저자
Rahimnejad, MaedehRabiee, NavidAhmadi, SepidehJahangiri, SepidehSajadi, S. MohammadAkhavan, OmidSaeb, Mohammad RezaKwon, WoosungKim, MunguHahn, Sei Kwang
DOI
10.1021/acsabm.1c00932
발행일
2021-12
유형
Review
저널명
ACS Applied Bio Materials
4
12
페이지
8110 ~ 8128