Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum

  • Song, YS; 
  • Kim, SH; 
  • Sa, JH; 
  • Jin, C; 
  • Lim, CJ; 
  • 외 1명
Citations

WEB OF SCIENCE

65
Citations

SCOPUS

80

초록

Fresh fruit bodies of Ganoderma lucidum were extracted with 70%. ethanol at room temperature. The extract (GL) showed significant anti-angiogenic activity, which was detected using a chick embryo chorioallantoic membrane assay. GL significantly inhibited LPS-induced NO production in RAW 264.7 macrophages. These results support the anti-tumor effect of Ganoderma lucidum. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

키워드

ganoderma lucidum; anti-angiogenic activity; nitric oxide; folk medicine; ANTIHERPETIC ACTIVITIES; L-ARGININE; SYNTHASE; COMBINATIONS; SUBSTANCES; GROWTH
제목
Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum
저자
Song, YS; Kim, SH; Sa, JH; Jin, C; Lim, CJ; Park, EH
DOI
10.1016/j.jep.2003.09.006
발행일
2004-01
유형
Article
저널명
Journal of Ethnopharmacology
권
90
호
1
페이지
17 ~ 20