Effects of Heat Stress-Induced Sex Hormone Dysregulation on Reproduction and Growth in Male Adolescents and Beneficial Foods
  • Ko, Seong-Hee
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WEB OF SCIENCE

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초록

Heat stress due to climate warming can significantly affect the synthesis of sex hormones in male adolescents, which can impair the ability of the hypothalamus to secrete gonadotropin-releasing hormone on the hypothalamic-pituitary-gonadal axis, which leads to a decrease in luteinizing hormone and follicle-stimulating hormone, which ultimately negatively affects spermatogenesis and testosterone synthesis. For optimal spermatogenesis, the testicular temperature should be 2-6 degrees C lower than body temperature. Heat stress directly affects the testes, damaging them and reducing testosterone synthesis. Additionally, chronic heat stress abnormally increases the level of aromatase in Leydig cells, which increases estradiol synthesis while decreasing testosterone, leading to an imbalance of sex hormones and spermatogenesis failure. Low levels of testosterone in male adolescents lead to delayed puberty and incomplete sexual maturation, negatively affect height growth and bone mineral density, and can lead to a decrease in lean body mass and an increase in fat mass. In order for male adolescents to acquire healthy reproductive capacity, it is recommended to provide sufficient nutrition and energy, avoid exposure to heat stress, and provide foods and supplements to prevent or repair testosterone reduction, germ cell damage, and sperm count reduction caused by heat stress so that they can enter a healthy adulthood.

키워드

testosteroneheat stressmale adolescentsdelayed pubertyincomplete sexual maturationreproductive failurerepairs of germ cell damagefoodssupplementsBONE-MINERAL DENSITYTESTOSTERONE DEFICIENCYOXIDATIVE STRESSHYPOGONADAL MENNEGATIVE IMPACTSEMEN QUALITYMUSCLE MASSMELATONININCREASESDNA
제목
Effects of Heat Stress-Induced Sex Hormone Dysregulation on Reproduction and Growth in Male Adolescents and Beneficial Foods
저자
Ko, Seong-Hee
DOI
10.3390/nu16173032
발행일
2024-09
유형
Review
저널명
Nutrients
16
17