HPLC-UV를 이용한 천마의 Gastrodin과 Gastrodigenin의 동시분석법 확립

Simultaneous determination of gastrodin and gastrodigenin in gastrodia elata by HPLC-UV
  • 강교빈; 
  • 전진범; 
  • 유귀재; 
  • 권은아; 
  • 윤준원; 
  • 외 5명
Citations

SCOPUS

4

초록

Gastrodia elata has been widely used as a traditional medicinal herb. However, in Korean Pharmacopeia, neither a marker constituent nor an analytical procedure for G. elata has been established. In this study, we suggest gastrodin and gastrodigenin as marker constituents of G. elata, and propose an analytical procedure for simultaneous quantification of these constituents by high-performance liquid chromatography-ultraviolet spectroscopy (HPLC-UV). The analytical method was validated for its linearity, precision, accuracy, and specificity. Based on the validated method, gastrodin and gastrodigenin in 14 commercial G. elata samples were quantified.

키워드

HPLC analysis; Gastrodia elata; Gastrodin; Gastrodigenin; Method validation
제목
HPLC-UV를 이용한 천마의 Gastrodin과 Gastrodigenin의 동시분석법 확립
제목 (타언어)
Simultaneous determination of gastrodin and gastrodigenin in gastrodia elata by HPLC-UV
저자
강교빈; 전진범; 유귀재; 권은아; 윤준원; 강병철; 김승현; 성상현; 장영표; 양희정
발행일
2017-09
저널명
생약학회지
권
48
호
3
페이지
232 ~ 236