상세 보기
- Kim, Kun-yong;
- Kim, Hwa Young;
- Kim, Jae Hyeong;
- Lee, Chul-Ho;
- Kim, Do-Hyung;
- ... Yoon, Sukjoon;
- ... Kim, Keun Il;
- ... Yang, Young;
- 외 6명
WEB OF SCIENCE
68SCOPUS
77초록
CTRP1, a member of the CTRP superfamily, consists of an N-terminal signal peptide sequence followed by a variable region, a collagen repeat domain, and a C-terminal globular domain. CTRP1 is expressed at high levels in adipose tissues of LPS-stimulated Sprague-Dawley rats. The LPS-induced increase in CTRP1 gene expression was found to be mediated by TNF-alpha and IL-1 beta. Also, a high level of expression of CTRP1 mRNA was observed in adipose tissues of Zucker diabetic fatty (falfa) rats, compared to Sprague-Dawley rats in the absence of LPS stimulation. These findings indicate that CTRP1 expression may be associated with a low-grade chronic inflammation status in adipose tissues. (c) 2006 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
키워드
- 제목
- Tumor necrosis factor-alpha and interleukin-1 beta increases CTRP1 expression in adipose tissue
- 저자
- Kim, Kun-yong; Kim, Hwa Young; Kim, Jae Hyeong; Lee, Chul-Ho; Kim, Do-Hyung; Lee, Young Ho; Han, Seung Hyun; Lim, Jong-Seok; Cho, Dae Ho; Lee, Myeong-Sok; Yoon, Sukjoon; Kim, Keun Il; Yoon, Do-Young; Yang, Young
- 발행일
- 2006-07
- 유형
- Article
- 저널명
- FEBS Letters
- 권
- 580
- 호
- 16
- 페이지
- 3953 ~ 3960