우리나라에서의 천식 및 만성폐쇄성폐질환 치료제 처방 양상
Drug Prescribing Patterns for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease in Korea
  • 장진경
  • 김해숙
  • 손현순
  • 박찬미
  • 김주상
  • ... 조정환
  • 외 3명
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초록

Purpose: The aim of this study was to investigate drug prescription patterns for the treatment of asthma and chronicobstructive pulmonary disease (COPD) patients in Korea. Methods: Ambulatory adult patients who were diagnosed andreceived treatment for the asthma (ICD-10 code J45) or COPD (ICD-10 code J44) from January 2009 to September2011 in two independent secondary hospitals in Korea were enrolled in this study. Prescribed drug lists were generatedbased on the evidence-based guidelines and prescribed drug dosage forms were identified from the patient medicalrecords and computerized drug prescription databases of the study centers. Results: Total numbers of asthma andCOPD patient enrolled in this study were 2,432 and 2,615, respectively. Individual prescription-based accumulated numbersof patient were 12,021 for asthma and 16,584 for COPD. The most commonly prescribed three drugs were oralpredisolone, oral formoterol and oral montelukast for asthma and oral formoterol, oral doxofylline and inhaled tiotropiumfor COPD. Frequencies of oral drugs were 83.4% and 63.3% while inhalers were 16.4% and 30.2%, for asthmaand COPD, respectively. Conclusion: The oral treatment was prescribed more in asthma and COPD patients than inhalers. To enhance the compliance of evidence-based guidelines for these chronic airway diseases, more realistic and specificstrategies to increase the use of inhalers recommended as primary treatment options for asthma and COPD wouldbe required.

키워드

asthmachronic obstructive pulmonary diseaseevidence-based guidelinesinhalers
제목
우리나라에서의 천식 및 만성폐쇄성폐질환 치료제 처방 양상
제목 (타언어)
Drug Prescribing Patterns for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease in Korea
저자
장진경김해숙손현순박찬미김주상정복현지은희조정환신현택
발행일
2014-03
저널명
한국임상약학회지
24
1
페이지
26 ~ 32