Synthesis and vanilloid receptor antagonist activity of 2-hydroxy-5-(3-phenethylthiocarbamoyloxypentyl)benzoic acid methyl ester
Synthesis and vanilloid receptor antagonist activity of 2-hydroxy-5-(3-phenetiiylthiocarbamoyloxypentyl)benzoic acid methyl ester
  • 박주현
  • 김희두
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초록

2-Hydroxy-5-(3-phenethylthiocarbamoyloxypentyl)benzoic acid methyl ester(2) was designed, synthesized and evaluated as a vanilloid receptor antagonist. Compound 2 did not show an antagonist activity up to 30 μM concentration in ^(45)Ca^(2+) -influx assay.

제목
Synthesis and vanilloid receptor antagonist activity of 2-hydroxy-5-(3-phenethylthiocarbamoyloxypentyl)benzoic acid methyl ester
제목 (타언어)
Synthesis and vanilloid receptor antagonist activity of 2-hydroxy-5-(3-phenetiiylthiocarbamoyloxypentyl)benzoic acid methyl ester
저자
박주현김희두
발행일
2005-02
저널명
약학논문집-숙명여자대학교
22
페이지
16 ~ 20