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수종동물의 췌장조직내 NO Synthase 활성도 및 Methylarginines 함량
NO Synthase Activities and Methylarginines Contents in the Pancreatic Tissues of Various Animals
- 김용기;
- 박승희;
- 남석우;
- 서동완;
- 홍성렬;
- 외 1명
초록
The activities of nitric oxide synthase and the contents of methylarginines were investigated in the pancreatic tissues of various animals by citrulline-forming method and HPLC, respectively. The high level of in vitro NO synthase activity was detected in chicken pancreas whereas MMA, the strong competitive inhibitor for NO synthase, was detected as trace in the same tissue. On the other hand, the low level of NO synthase activity was observed in the porcine pancreas while the contents of MMA were high. However, it was not possible to find any relationship between NO synthase activities and the contents of dimethylarginines at present time. D'MA was equally distributed among the pancreatic tissues of various animals but DMA was not.
키워드
Nitric oxide synthase; N G -monomethyl-L-arginine; N G , N G -dimethyl-L-arginine; N G , N ′ G -dimethyl-L-arginine
- 제목
- 수종동물의 췌장조직내 NO Synthase 활성도 및 Methylarginines 함량
- 제목 (타언어)
- NO Synthase Activities and Methylarginines Contents in the Pancreatic Tissues of Various Animals
- 저자
- 김용기; 박승희; 남석우; 서동완; 홍성렬; 이향우
- 발행일
- 1994-04
- 저널명
- 약 학 회 지
- 권
- 38
- 호
- 2
- 페이지
- 184 ~ 190
- 언어
- KOR
- 출판사
- 대한약학회
- 발행국가
- 대한민국
- 분량
- 7 페이지
- ISSN
- E 2383-9457
P 0377-9556