ScholarWorks@숙명여자대학교

초록

In this study, we prepared a lotion containing Gymnema sylvestre Leaf Extract (GSLE) and evaluated its stability, safety, and usability. To assess stability, a series of scientific evaluations were conducted, including centrifugation testing and heat-cool cycling. Following the application of the Lycon, 5% GSLE lotion on the skin, a skin patch test was conducted to detect the presence of erythema in the designated patch area, in accordance with the established guidelines provided by the International Contact Dermatitis Research Group (ICDRG). Using a 10-point scale, the level of satisfaction resulting from actual usage was assessed. The stability of both the vehicle and the 5% GSLE lotion was found to be intact in terms of their physical and chemical properties. No adverse skin reactions were observed in any of the groups tested, which included the vehicle, Lycon lotion, and 5% GSLE lotion. Furthermore, when considering efficacy, functionality, and usability, the 5% GSLE lotion demonstrated the highest value. In terms of absorption, moisturization, smoothness, and calming effects, the Lycon lotion exhibited relatively lower performance compared to both the vehicle and the 5% GSLE lotion. Across all evaluation criteria, the 5% GSLE lotion was found to provide an excellent user experience.

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