Anti-angiogenic activity of the methanol extract and its fractions of Ulmus davidiana var. japonica

  • Jung, Hyun-Joo; 
  • Jeon, Hye-Jin; 
  • Lim, Eun-Ju; 
  • Ahn, Eun-Kyoung; 
  • Song, Yun Seon; 
  • 외 4명
Citations

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30
Citations

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34

초록

This study aimed to elucidate anti-angiogenic activity of Ulmus davidiana var. japonica that has been widely used in folk medicine. The methanol extract (UDE) of Uhnus davidiana var. japonica concentration-dependently displayed a strong inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. The n-butanol fraction of UDE and subsequent 30% MeOH subtraction were identified to be most responsible for the anti-angiogenic activity. (c) 2007 Elsevier Ireland Ltd. All rights reserved.

키워드

Ulmus davidiana var. japonica; angiogenesis; anti-angiogenic; chorioallantoic membrane; Ulmaceae; MUSHROOM PHELLINUS-LINTEUS; TUMOR-GROWTH; PHARMACOLOGICAL-ACTIVITIES; ANTIANGIOGENIC ACTIVITY; GARDENIA-JASMINOIDES; NATURAL-PRODUCT; IN-VITRO; INHIBITION; MECHANISMS; COMPOUND
제목
Anti-angiogenic activity of the methanol extract and its fractions of Ulmus davidiana var. japonica
저자
Jung, Hyun-Joo; Jeon, Hye-Jin; Lim, Eun-Ju; Ahn, Eun-Kyoung; Song, Yun Seon; Lee, Sanghyun; Shin, Kuk Hyun; Lim, Chang-Jin; Park, Eun-Hee
DOI
10.1016/j.jep.2007.03.006
발행일
2007-06
유형
Article
저널명
Journal of Ethnopharmacology
권
112
호
2
페이지
406 ~ 409