A fluorescent probe for copper and hypochlorite based on rhodamine hydrazide framework

초록

A rhodamine derivative (1) was synthesized as a fluorescence turn-on probe for copper (Cu2+) and hypochlorite (CIO-). The probe gave a fluorescence turn-on change at 587 nm with a color change from colorless to pink in the presence of Cu2+ or ClO- ions in aqueous solution. It was found that the Cu2+ ion bound to 1 in a 1:1 stoichiometry and induced a spirolactam ring opening of the rhodamine moiety leading to a fluorescence turn-on, confirmed by Job's plot, ESI-Mass, and H-1 NMR analyses. In the presence of ClO- ion, probe 1 underwent a hypochlorite-mediated oxidation and hydrolysis to produce a ring-opened rhodamine B with a fluorescence enhancement, However, these changes were not monitored in case of other metal ions, anions, and reactive redox species, In addition, probe 1 can readily react with the ClO- to provide a distinct fluorescence enhancement along with a pink color even in the presence of various competitive species. (C) 2017 Elsevier Ltd. All rights reserved.

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