Arabidopsis thaliana homeobox 12 (ATHB12), a homeodomain-leucine zipper protein, regulates leaf growth by promoting cell expansion and endoreduplication
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hur, Yoon-Sun | - |
dc.contributor.author | Um, Ji-Hyun | - |
dc.contributor.author | Kim, Sunghan | - |
dc.contributor.author | Kim, Kyunga | - |
dc.contributor.author | Park, Hee-Jung | - |
dc.contributor.author | Lim, Jong-Seok | - |
dc.contributor.author | Kim, Woo-Young | - |
dc.contributor.author | Jun, Sang Eun | - |
dc.contributor.author | Yoon, Eun Kyung | - |
dc.contributor.author | Lim, Jun | - |
dc.contributor.author | Ohme-Takagi, Masaru | - |
dc.contributor.author | Kim, Donggiun | - |
dc.contributor.author | Park, Jongbum | - |
dc.contributor.author | Kim, Gyung-Tae | - |
dc.contributor.author | Cheon, Choong-Ill | - |
dc.date.available | 2021-02-22T11:46:29Z | - |
dc.date.issued | 2015-01 | - |
dc.identifier.issn | 0028-646X | - |
dc.identifier.issn | 1469-8137 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/10714 | - |
dc.description.abstract | Arabidopsis thaliana homeobox 12 (ATHB12), a homeodomain-leucine zipper class I (HD-Zip I) gene, is highly expressed in leaves and stems, and induced by abiotic stresses, but its role in development remains obscure. To understand its function during plant development, we studied the effects of loss and gain of function. Expression of ATHB12 fused to the EAR-motif repression domain (SRDX) - P-35S::ATHB12SRDX (A12SRDX) and P-ATHB12::ATHB12SRDX - slowed both leaf and root growth, while the growth of ATHB12-overexpressing seedlings (A12OX) was accelerated. Microscopic examination revealed changes in the size and number of leaf cells. Ploidy was reduced in A12SRDX plants, accompanied by decreased cell expansion and increased cell numbers. By contrast, cell size was increased in A12OX plants, along with increased ploidy and elevated expression of cell cycle switch 52s (CCS52s), which are positive regulators of endoreduplication, indicating that ATHB12 promotes leaf cell expansion and endoreduplication. Overexpression of ATHB12 led to decreased phosphorylation of Arabidopsis thaliana ribosomal protein S6 (AtRPS6), a regulator of cell growth. In addition, induction of ATHB12 in the presence of cycloheximide increased the expression of several genes related to cell expansion, such as EXPANSIN A10 (EXPA10) and DWARF4 (DWF4). Our findings strongly suggest that ATHB12 acts as a positive regulator of endoreduplication and cell growth during leaf development. | - |
dc.format.extent | 13 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | WILEY | - |
dc.title | Arabidopsis thaliana homeobox 12 (ATHB12), a homeodomain-leucine zipper protein, regulates leaf growth by promoting cell expansion and endoreduplication | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1111/nph.12998 | - |
dc.identifier.scopusid | 2-s2.0-84912027859 | - |
dc.identifier.wosid | 000345596700031 | - |
dc.identifier.bibliographicCitation | NEW PHYTOLOGIST, v.205, no.1, pp 316 - 328 | - |
dc.citation.title | NEW PHYTOLOGIST | - |
dc.citation.volume | 205 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 316 | - |
dc.citation.endPage | 328 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.subject.keywordPlus | SIZE CONTROL | - |
dc.subject.keywordPlus | KNOX GENES | - |
dc.subject.keywordPlus | S6 KINASE | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | STRESS | - |
dc.subject.keywordPlus | GIBBERELLIN | - |
dc.subject.keywordPlus | ELONGATION | - |
dc.subject.keywordPlus | TARGET | - |
dc.subject.keywordPlus | DIVISION | - |
dc.subject.keywordPlus | PATTERNS | - |
dc.subject.keywordAuthor | Arabidopsis thaliana homeobox 12 (ATHB12) | - |
dc.subject.keywordAuthor | cell expansion | - |
dc.subject.keywordAuthor | endoreduplication | - |
dc.subject.keywordAuthor | homeobox | - |
dc.subject.keywordAuthor | leaf development | - |
dc.identifier.url | https://nph.onlinelibrary.wiley.com/doi/full/10.1111/nph.12998 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Sookmyung Women's University. Cheongpa-ro 47-gil 100 (Cheongpa-dong 2ga), Yongsan-gu, Seoul, 04310, Korea02-710-9127
Copyright©Sookmyung Women's University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.