한방 발효주 주박 추출물의 미백 및 피부 주름 개선 효과
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이수민 | - |
dc.contributor.author | 이상진 | - |
dc.contributor.author | 권이영 | - |
dc.contributor.author | 백상훈 | - |
dc.contributor.author | 김종식 | - |
dc.contributor.author | 손호용 | - |
dc.contributor.author | 신우창 | - |
dc.date.available | 2021-02-22T11:47:04Z | - |
dc.date.issued | 2014-11 | - |
dc.identifier.issn | 1226-3311 | - |
dc.identifier.issn | 2288-5978 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/10769 | - |
dc.description.abstract | Oriental herbal liquor (Yakju) is a type of Korean traditional alcoholic beverage that uses Nuruk and oriental herbs for fermentation. The purpose of this study was to develop cosmetic ingredients using Jubak, which is a by-product of alcoholic fermentation of oriental herbal liquor. To investigate antioxidant, whitening, and anti-aging effects of Jubak, we prepared extract of Jubak and its solvent fractions. Ethyl acetate fraction (KSD E4-3) showed the most prominent free radical [1,1-diphenyl-2-picrylhydrazyl (DPPH)] scavenging activity (SC50: 0.75 mg/mL). KSD E4-3 significantly inhibited in vitro mushroom tyrosinase activity (IC50: 0.82 mg/mL) and reduced the melanin contents in mouse melanoma melanocyte, B16F10 cells. KSD E4-3 down-regulated protein expression of tyrosinase related proteins (TRP)-1, -2, which play key roles in melanogenesis. For anti-aging effects, inhibition of matrix metalloproteinase (MMPs) expression was evaluated using human keratinocyte, HaCaT cells. Treatment of HaCaT cells with KSD E4-3 reduced expression of MMP-1, -2, -9 and inhibited proteolytic activities of MMP-2, -9. These results suggest that KSD E4-3 induces down-regulation of cellular melanogenesis and protects against photoaging induced by UVB-induced damage. Thus KSD E4-3 could potentially be a valuable cosmetic ingredient. © 2014, Korean Society of Food Science and Nutrition. All rights received. | - |
dc.format.extent | 6 | - |
dc.language | 한국어 | - |
dc.language.iso | KOR | - |
dc.publisher | Korean Society of Food Science and Nutrition | - |
dc.title | 한방 발효주 주박 추출물의 미백 및 피부 주름 개선 효과 | - |
dc.title.alternative | Skin whitening and anti-wrinkle effects of extract from Jubak of oriental herbal liquor | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3746/jkfn.2014.43.11.1695 | - |
dc.identifier.scopusid | 2-s2.0-84914117763 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Society of Food Science and Nutrition, v.43, no.11, pp 1695 - 1700 | - |
dc.citation.title | Journal of the Korean Society of Food Science and Nutrition | - |
dc.citation.volume | 43 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1695 | - |
dc.citation.endPage | 1700 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001931812 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Anti-melanogenesis | - |
dc.subject.keywordAuthor | Anti-wrinkle | - |
dc.subject.keywordAuthor | Antioxidant | - |
dc.subject.keywordAuthor | Jubak | - |
dc.subject.keywordAuthor | Oriental herbal liquor | - |
dc.identifier.url | http://www.dbpia.co.kr/journal/articleDetail?nodeId=NODE02502927&language=ko_KR | - |
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