Detailed Information
Cited 0 time in 
Cited 0 time in 
Cited 0 time in
Metadata Downloads
SK-Hep1 인체 간암 세포에서 Luteolin에 의한 TRAIL 저항성 감소 효과
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | 김은영 | - |
| dc.contributor.author | 김안근 | - |
| dc.date.available | 2021-02-22T13:02:24Z | - |
| dc.date.issued | 2012-02 | - |
| dc.identifier.issn | 0377-9556 | - |
| dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/12348 | - |
| dc.description.abstract | In this study, we examined the effect of luteolin to enhance TRAIL-induced anticancer effect in SK-Hep1 cells. We found that combined use of TRAIL with luteolin markedly enhanced the cytotoxicity compared to either agent alone by inducing apoptosis. Furthermore, combined treatment of TRAIL with luteolin significantly induced activation of death receptor pathway-related proteins as well as PARP-cleavage and activation of effector caspases. Also, our result indicated that upregulation of DR4 and DR5 by luteolin combination may contribute to enhanced susceptibility of SK-Hep1 cells to TRAIL. | - |
| dc.format.extent | 7 | - |
| dc.language | 한국어 | - |
| dc.language.iso | KOR | - |
| dc.publisher | 대한약학회 | - |
| dc.title | SK-Hep1 인체 간암 세포에서 Luteolin에 의한 TRAIL 저항성 감소 효과 | - |
| dc.title.alternative | Sensitization of TRAIL-resistant SK-Hep1 Human Hepatocellular Carcinoma Cells by Luteolin | - |
| dc.type | Article | - |
| dc.publisher.location | 대한민국 | - |
| dc.identifier.bibliographicCitation | 약 학 회 지, v.56, no.1, pp 35 - 41 | - |
| dc.citation.title | 약 학 회 지 | - |
| dc.citation.volume | 56 | - |
| dc.citation.number | 1 | - |
| dc.citation.startPage | 35 | - |
| dc.citation.endPage | 41 | - |
| dc.identifier.kciid | ART001641524 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | kci | - |
| dc.subject.keywordAuthor | TRAIL | - |
| dc.subject.keywordAuthor | luteolin | - |
| dc.subject.keywordAuthor | apoptosis | - |
| dc.subject.keywordAuthor | death receptors | - |
| dc.identifier.url | https://scholar.kyobobook.co.kr/article/detail/4010024509533 | - |
- Files in This Item
- Go to Link
- Appears in
Collections - 약학대학 > 약학부 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.