Inhibition of pentylenetetrazole-induced seizure in mice by using a 4 Hz magnetic field: a comparative study with a 60 Hz magnetic field
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Won-Hee | - |
dc.contributor.author | Chae, Young-Joo | - |
dc.contributor.author | Soh, Kwang-Sup | - |
dc.contributor.author | Lee, Byung-Cheon | - |
dc.contributor.author | Pyo, Myoung-Yun | - |
dc.date.available | 2021-02-22T13:03:45Z | - |
dc.date.issued | 2012-12 | - |
dc.identifier.issn | 1536-8378 | - |
dc.identifier.issn | 1536-8386 | - |
dc.identifier.uri | https://scholarworks.sookmyung.ac.kr/handle/2020.sw.sookmyung/12410 | - |
dc.description.abstract | We investigated the comparative effects of 4 and 60 Hz magnetic fields on pentylenetetrazole (PTZ)-induced seizure in mice. For this study, we measured the latent time to seizure, seizure duration, and lethality induced by PTZ in mice exposed to 4 and 60 Hz magnetic fields (MF) for 30 min. Compared to sham-exposed controls, the latent time to tail twitching and seizure in the 4 Hz MF group was significantly decreased while the latent time to seizure in the 60 Hz MF group was significantly increased. The seizure duration in the 4 Hz MF group was significantly decreased while that in the 60 Hz MF group was significantly increased. More importantly, while the mice exposed to a 60 Hz MF experienced significantly increased lethality after seizure convulsion, those exposed to a 4 Hz MF showed no lethality, with a shortening of the duration of seizure. This beneficial effect of a 4 Hz MF on seizure has the same implication as the anti-oxidative effects of a 4 Hz MF observed in our previous work. The results of our current and previous works indicate that a 4 Hz MF may be used as a therapeutic physical agent for the treatment of oxidative stress-induced diseases, including seizure, with or without chemical drugs. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | INFORMA HEALTHCARE | - |
dc.title | Inhibition of pentylenetetrazole-induced seizure in mice by using a 4 Hz magnetic field: a comparative study with a 60 Hz magnetic field | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.3109/15368378.2012.662191 | - |
dc.identifier.scopusid | 2-s2.0-84868695935 | - |
dc.identifier.wosid | 000310808500005 | - |
dc.identifier.bibliographicCitation | ELECTROMAGNETIC BIOLOGY AND MEDICINE, v.31, no.4, pp 293 - 298 | - |
dc.citation.title | ELECTROMAGNETIC BIOLOGY AND MEDICINE | - |
dc.citation.volume | 31 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 293 | - |
dc.citation.endPage | 298 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Life Sciences & Biomedicine - Other Topics | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Biology | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.subject.keywordPlus | DNA STRAND BREAKS | - |
dc.subject.keywordPlus | ACUTE EXPOSURE | - |
dc.subject.keywordPlus | BRAIN-CELLS | - |
dc.subject.keywordPlus | MOUSE-BRAIN | - |
dc.subject.keywordPlus | CHEMILUMINESCENCE | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | APOPTOSIS | - |
dc.subject.keywordPlus | RATS | - |
dc.subject.keywordAuthor | 4 Hz magnetic field | - |
dc.subject.keywordAuthor | 60 Hz magnetic field | - |
dc.subject.keywordAuthor | Seizure | - |
dc.subject.keywordAuthor | Pentylenetetrazole | - |
dc.subject.keywordAuthor | Oxidative stress | - |
dc.identifier.url | https://www.tandfonline.com/doi/full/10.3109/15368378.2012.662191 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Sookmyung Women's University. Cheongpa-ro 47-gil 100 (Cheongpa-dong 2ga), Yongsan-gu, Seoul, 04310, Korea02-710-9127
Copyright©Sookmyung Women's University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.